I have probably changed out over 10,000 tires over the years and have never seen the inside if a tire rot due to anything. In fact, even very old tires look brand new on the inside. Some tires, that have been run under inflated, tend to sluff off rubber on the inside and that will sometimes roll up into little rubber balls. I've seen tires loaded with very corrosive "Fix a Flat" but once you clean that out, still look brand new.
Its a snake oil gimmic.... and it works doesn't it