The fundamental issue is funding your adventure. You will need to budget US$100/day for gas, food, drinks, more drinks, ice, camping fees, propane etc. Some days are more, some are less but that is $36,500 for ONE year and does not include consumables and repairs, insurance, DMV fees, storage fees, mail service, medical and dental costs etc.
A $45K bankroll would be needed to safely cover a yearlong country-wide high mileage tour to fully experience whats out there without having to constantly worry about money.