With maybe 5-6 times the size of the contact patch of a motorcycle tire's on the flat and level, there are considerably more than nuanced differences in low speed handling between the two.
Whereas the fat meat that is a 240 motorcycle tire is a bit of a handful to maneuver at really low speeds (say under 10 mph) the car tire can provide the rider with a real wrestling match comparatively. Although any bike tire over the 180 size, let's say, is going to provide the user with a more and more pronounced tussle as tire sizes increase on either dirt or gravel roads, on heavily cambered or rain-grooved roadways and on steel-grated bridge ways, for example, the same effect will only become more pronounced, magnified, one could say, with the flat-treaded car tire. This is not to say that an experienced rider cannot become used to or isn't able to accomodate for such deleterious effects.
At slightly higher low speeds, lets say 11-39 mph, one will take notice of the car tire's constant requirement for increased rider input, both in overall effort as well as in the amount of counter-steering required to make all but the sublest turns effectively. Additionally, as speed increases, a good rider will notice and factor in the extra response time that comes with quick maneuvering, i.e. the car tire is slower to respond to a rider's input in virtually any given situation involving emergency or evasive maneuvers, a fact that any intelligent rider will also factor in should they choose to ride on the Darkside. Steering transition or "flickability" as I like to call that handling characteristic, is also noticeably diminished or compromised when utilizing a CT on the rear and the difference difference here becomes progressively more stark as one's speed and the amount of twists in the road increase.
The above is strictly my opinion based upon my own personal experience gained on both types of tires. At this point I have had nearly the same amount of time on my old Toyo Proxes T1R 225 50/16 as I have had on the OEM motorcycle tire or about 7,000 miles on each. I will probably try the B'stone high endurance tire or the Avon Cobras next. There is no way I will return to a car tire on the rear of this particular bike in spite of its, IMO, very limited advantages over a MT.