I have had an idea of a series that would move across country as the season kicks in. The schedule would allow someone to do the whole ride, start to finish, or just do one or more of the multiple locations, for those that still have jobs or other anchors. This would really make RAA live up to its name.
But that idea is prob'ly just a daydream....
Practically speaking, the conventional "home base" location is still the best for simplicity.
I could easily envision an Appalachian venue, other than the Smokies. Nothing wrong with the roads there but it's crowded compared to areas around say Beckley or Lewisburg WV. BUT my criteria is the riding, I don't give a crap about sightseeing or alternative activities...not everyone is like me.
If I had to nail it down to one location in the country, I'd vote for northern California.
At either Northern CA or mid-Appalachians, it would be easy to have 2 or 3 locations if you wanted a rolling venue.
2 days @ 3 different stops or 3 days @ 2 different stops are possibilities.