Overall probably yes, but mostly just different. There's nonstop grand landscapes and vistas, and of course that can be breathtaking. But it can also seem so far away at times, like a big painting you're riding by. And it's so wide open a lot of the roads are just long straight stretches through the valleys and hills with the occasional mountain pass.
Some of the best riding I've ever done is through heavily wooded small curvy roads, and there's plenty of that in the Midwest. You've got amazing riding from just past Madison to Minnesota, and really that's as far for you as I have to go for some of the really great rides out here.
It's probably from growing up in Indiana. As much as it can impress out here, I'll always miss the trees in the east. Plus riding through open corn country will always hit home for me, plus you have the lakefront and oh yeah… Michigan! Tons to enjoy.